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Bulletin of Pure and Applied Sciences-Zoology (Started in 1982)
eISSN:2320-3188
pISSN: 0970-0765
Impact Factor: 6.994 (Cosmos)
DOI: 10.5958/2320-3188
Editor-in-Chief:  Prof. Dr. Vineeta Shukla
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Article Details

Bulletin of Pure and Applied Sciences-Zoology (Started in 1982)
Year : 2022, Volume & Issue : BPAS-Zoology 41A(1), JAN-JUN 2022
Page No. : 56-66, Article Type : Original Aticle
Article DOI : 10.5958/2320-3188.2022.00008.0

Does Time restriction feeding reverse the High fat diet induced obesity in Drosophila melanogaster?

*Mohammad S. Al-Maqashah1, V. Shakunthala2, Damini CS3
Author’s Affiliation : 1Ph.D. Research Scholar, Chronobiology lab, Department of Studies in Zoology, Manasagangothri, University of Mysore, Mysuru, Karnataka 570005, India. E-mail: msqo2000@yahoo.com 2Associate Professor, Department of Studies in Zoology, Manasagangothri, University of Mysore, Mysuru, Karnataka 570005, India. E-mail: drshakunthalav2@gmail.com 3Ph.D. Research Scholar, Chronobiology lab, Department of Studies in Zoology, Manasagangothri, University of Mysore, Mysuru, Karnataka 570005, India. E-mail: damini.c.s@gmail.com

Corresponding Author : V. Shakunthala Associate Professor, Department of Studies in Zoology, Manasagangothri, University of Mysore, Mysuru, Karnataka 570005, India. ,
E-Mail:- drshakunthalav2@gmail.com


Abstract

Obesity and its co-morbidity are the most challenging tasks for the current health care system. It is a multifactorial disorder either due to genetic predisposition, high calorie-dense diet, circadian disruption, etc. Circadian disruption is due to people’s altered lifestyle choices have resulted in increased obesity that can be measured in terms of lipid profiles, overweight, and endogenous antioxidant level. As consequence of this increased diabetes and cardiovascular problems among the current generation. The present study is an attempt to understand the importance of disciplined lifestyle and eating at the right time. Many studies in this regard have revealed time-restriction feeding and its benefits. The current study aims to investigate the adverse effects of a high-fat diet on odd-time eating and high-fat diet with that of time-restriction feeding (TRF). To address this problem, we choose Drosophila melanogaster flies that were fed with different food regime as high-fat diet (HFD), a normal diet (ND) as a control, HFD+TRF and ND+TRF. The biochemical assays were used to detect obesity, the stress and TRF normalizes the triglyceride level to reduce endogenous antioxidants in the HFD group was observed and TRF has an effective response to obesity by reducing body adiposity caused by a high-fat diet.

How to cite this article: Al-Maqashah MS, Shakunthala V., Damini CS. (2022). Does Time restriction feeding reverse the High fat diet induced obesity in Drosophila melanogaster? Bulletin of Pure and Applied Sciences-Zoology, 41A (1), 56-66.

Keywords

Drosophila melanogaster,TRF, HFD, SOD, catalase
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