ABOUT US
JOURNALS
ANNUAL SUBSCRIPTION
SUBSCRIPTION ORDER FORM
BUY ONLINE

Bulletin of Pure and Applied Sciences-Zoology (Started in 1982)
eISSN:2320-3188
pISSN: 0970-0765
Impact Factor: 6.994 (Cosmos)
DOI: 10.5958/2320-3188
Editor-in-Chief:  Prof. Dr. Vineeta Shukla
About Journal More Archive Visit IndianJournals.com
Current Issue
Archive
Author Guidelines 2022
Journal's Ethics & Policies
Editorial Board
Reviewer Board
Indexing
UGC Approved Journal (Indexed in Web of Science )
Article Details

Bulletin of Pure and Applied Sciences-Zoology (Started in 1982)
Year : 2022, Volume & Issue : BPAS-Zoology 41A(1), JAN-JUN 2022
Page No. : 149-157, Article Type : Review Aticle
Article DOI : 10.5958/2320-3188.2022.00018.3 Article Info: Received on 21.08.2021 Revised on 26.12.2021 Accepted on 15.01.2022 Published on 15.06.2022

Oxidative Stress in Plasmodium: Role of Glutathione Revisited

Gaurav Kapoor
Author’s Affiliation : Department of Zoology, Rajkiya Kanaya Mahavidalaya (RKMV), Shimla-171001, Himachal Pradesh, India.

Corresponding Author : Gaurav Kapoor Department of Zoology, Rajkiya Kanaya Mahavidalaya (RKMV), Shimla-171001, Himachal Pradesh, India.,
E-Mail:-drgauravkapur.hpu@gmail.com


Abstract

Malaria is still one of the three leading infectious disease in the world. Plasmodium, unicellular eukaryotic parasite responsible for the disease is under immense oxidative stress during the erythrocytic stages of its life cycle. The parasite overcomes the oxidative stress generated endogenously and by host immune system through its antioxidant and redox systems. Plasmodium possesses glutathione and thioredoxin redox systems with overlapping but distinct functions that help it to maintain redox state. Glutathione is the most abundant low molecular weight thiol redox buffer in all living cells that is detrimental for the maintenance of intracellular redox status. Glutathione functions as an antioxidant protecting cells against the deleterious effects of oxidant free radicals and also in detoxification process reactions in parasite. Interfering with glutathione redox system of parasite can be a novel way to combat the disease. The present review describes the recent findings in role and mechanism of glutathione in maintaining the redox status during oxidative stress in infection with Plasmodium.

How to cite this article: Kapoor G.  (2022). Oxidative Stress in Plasmodium: Role of Glutathione Revisited. Bulletin of Pure and Applied Sciences-Zoology, 41A (1), 149-157.

Keywords

Malaria, Plasmodium, Glutathione, Antioxidant, Oxidative stress.
Buy Now

All rights reserved. Website Designed and Maintained by LASERWEBMAKER.COM

Publisher Ethics & Policies    |    Downloads    |    Article Submission   |    Payment    |    Our Team    |    Contact Us    

Website Visitors