Applications of T1 Subtraction Imaging in Non – Vascular Magnetic Resonance Imaging

Abstract

Background: Subtraction imaging of T1 post contrast sequence is a useful imaging technique in assessing the enhancement patterns of intrinsically T1 hyperintense lesions. This helps in better characterization of lesions. This study shows the utility of T1 post contrast subtraction sequence in various pathologies. Aims: To study the applications of T1 subtraction imaging in nonvascular magnetic resonance imaging. Settings and Design: Prospective observational study, conducted in the Department of Radiodiagnosis, Kasturba Medical College, Manipal. The patients were subjected to MRI imaging on Philips Achieva 1.5 T MRI and GE Signa HDxT 1.5 Tesla MRI. Methods and Materials: Total number of 21 patients were included for the study based on strict inclusion and exclusion criteria. Patients harbouring T1 hyperintense lesions in various parts were included and were subjected to T1 subtraction imaging. Statistical analysis: The acquired data was analysed using the statistical package SPSS version 20. Cohen’s Kappa measure of agreement was performed for each variable.Results: Study included 7 cases of musculoskeletal system, 6 cases of brain, 6 of pelvis and 2 cases of liver. There was good agreement is assessing enhancement pattern between two observers. Inter-observer variability was seen in only 2 cases. Lesion characterization was found to be better in subtracted images.Conclusion:T1 post contrast subtracted imaging is useful technique to assess enhancement pattern in intrinsically T1 hyperintense lesions and should be used on a routine basis