Formulation development and evaluation of Bexagliflozin loaded nano emulsion

Abstract

The goal of the current endeavour is to identify and create a bexagliflozin small emulsion that can effectively cure diabetes. Bexagliflozin is advised in order to assist people with diabetes with type 2 diabetes improve the control of their glucose levels when combined with a good diet and regular exercise. Additionally, bexagliflozin's absorption through the mouth is limited (in the range of fifty to seventy percent). The purpose of this effort was to create nanoemulsion formulations incorporating bexagliflozin and assess their effectiveness in vitro. nanoemulsion made up of distilled water, Tween eighty, a co-surfactant (The polyethylene glycol 400), various oils (oleic acid), containing 0.01% bexagliflozin. The ultrasonic technologies for processing is used to create a variety of water-in-oil nanoemulsion. In vitro drug release studies, stability studies, thermodynamic durability tests, FTIR, pH, and viscosity were conducted on the nano-emulsion formulations.