Biological Evaluation of Benzothiazole Derivatives: A Comprehensive Review

Abstract

Benzothiazole derivatives represent a unique class of heterocyclic compounds with wide-ranging biological activities that have garnered significant interest in medicinal chemistry. This review provides an in-depth analysis of the synthesis, biological evaluation, mechanisms of action, and therapeutic applications of benzothiazole derivatives. By summarizing recent research on their antimicrobial, anticancer, anti-inflammatory, antioxidant, neuroprotective, and other pharmacologically relevant properties, we aim to highlight the therapeutic potential of benzothiazole derivatives and discuss future directions for development.