Current Review On Nanosponges Gel For Effective Treatment Of Fungal Disease

Abstract

Fungal infections represent a significant global health challenge, with more than 600 fungal species associated with humans as either commensals or pathogens. Environmental changes and modern lifestyle factors have facilitated the emergence and spread of fungal diseases, making effective prevention and treatment strategies crucial. Topical therapy remains a preferred approach for treating skin infections due to its direct action and reduced systemic side effects. Econazole nitrate, an imidazole antifungal, is commonly used in various topical formulations. Recent advances in drug delivery have introduced nanosponges innovative carriers that enhance drug solubility, stability, and bioavailability. This review focuses on the development and application of nanosponges for the delivery of antifungal drugs, highlighting their advantages in treating fungal infections. By encapsulating drugs in nanosponges, sustained release and targeted delivery can be achieved, improving therapeutic efficacy and patient compliance.