A Comparative Evaluation of Antimicrobial Activity 0f Magnolia Bark Extract, Triphala Extract and Commercially Available Pediatric Toothpastes: An In-Vitro Study

Abstract

Background: Dental caries affects individuals of all ages. Lactobacilli have been recognized as key contributors to human dental caries for over a century. Magnolia bark extract and Triphala extract, renowned for their wide range of pharmacological properties, have not been extensively studied or compared against each other. Hence, this study aimed to evaluate the antimicrobial efficacy of Magnolia bark extract, Triphala extract, fluoridated, and non-fluoridated toothpastes on Lactobacilli. Materials and Method: Magnolia bark extract, Triphala extract, fluoridated, and non-fluoridated toothpastes were prepared at concentrations of 50%, 25%, and 12.5%. Antimicrobial activity was assessed using the agar well diffusion method by measuring zones of inhibition. Results: At concentrations of 50%, 25%, and 12.5%, Magnolia bark extract showed zones of inhibition of 20.33 mm, 16.66 mm, and 13 mm, respectively. Triphala extract showed zones of 17.66 mm, 13 mm, and 12.33 mm. Fluoridated toothpaste showed zones of 18 mm, 14.66 mm, and 12.33 mm, while non-fluoridated toothpaste showed zones of 15.66 mm, 12.33 mm, and 10.33 mm. Conclusion: The study findings highlight the superior antimicrobial activity of magnolia bark extract compared to triphala, fluoridated, and non-fluoridated toothpaste.  Incorporating magnolia bark extract into dentifrices could prove beneficial in inhibiting caries-causing microorganisms and promoting oral health.