Solid state synthesis of 5–anilino–3–(3,5–dimethylpyrazol–1–yl)–1,2,4 thiadiazoles

Abstract

We wish to report the synthesis of 5–anilino–3–(3,5–dimethylpyrazol–1–yl)–1,2,4–thiadiazoles by a solid state, mechanochemical oxidative cyclization of 3,5–dimethyl–1–[N–(N’ arylthiocarbamoyl) amidino] pyrazoles, which in turn have also been accessed through a solvent free, green technique.