DNA recognitions of Benzimidazole based Bendamustine, Albendazole, and Mebendazole: a Molecular Docking Study

Abstract

A few very well-known marketed drugs-Bendamustine, Albendazole, and Mebendazole are studied whether the drugs can bind with two different oligonucleotides or not. Molecular docking study was employed to find the capability of these drugs towards two entirely different DNA sequences. Due to the three-dimensional structures; those drugs are found to bind differentially with DNA duplexes. The other functional possibilities of known drugs with DNA recognitions might be helpful in drug repurposing purposes with the findings of present study.