A review on Flurbiprofen: Therapeutic challenges in Emerging Active Metabolizing Biphenyl

Abstract

Flurbiprofen is chemically 2-(3- fluoro-4 Biphenyl) propanoic acid. It is a nonsteroidal anti-inflammatory drug (NSAID) which has also been found effective in the treatment of rheumatoid arthritis and degenerative joint diseases. R-Flurbiprofen has been utilized in the treatment of neoplastic diseases such as breast cancer, lung cancer, prostate cancer as well as cystic fibrosis and Alzheimer's disease. Flurbiprofen has shown an excellent therapeutic action against many diseases and has been reported to acquire anti-inflammatory, analgesic, antipyretic, antimicrobial, antipyretics, antithrombotic, antinociceptive, anti-tumour and radio protective activities. The derivatives of flurbiprofen have been reported to contribute significantly in controlling various diseases. In this context, the present report deals with the summary of therapeutic uses of Flurbiprofen and its various combinations that play an important role in controlling painful and deadly diseases along with reducing serious side effects caused by the typical medical treatment. It is also used in the treatment of rheumatoid arthritis and osteoarthritis.